I would appreciate getting folks thoughts on the below table. Trying to ensure alignment to EMA/CHMP/CVMP/QWP/850374/2015 - Guideline on the sterilization of the medicinal product, active substance, excipient and primary container (effective 01 October 2019)
 

Item	Phase I	Phase II	Phase III	Commercial
Bacteria retention in water or saline lactose broth (SLB) with integrity test correlation in water or solvent	x	x	-	-
Bacteria retention in product	-	-	x	x
Chemical compatibility, effects on the filter integrity	x*	x*	x	x
Extractables & Leachables (model solvent – laboratory conditions)	x	x	-	-
Extractable & Leachables (product specific fluids)	-	-	x**	x**
Sterilization method, effects on filter integrity	x***	x***	x	x
Integrity test (water or solvent)	x	x	-	-
Integrity test method selection (product)	-	-	x	x
Toxicity test***	x	x	x	x
Fit for use	x***	x***	x	x

* Data can be taken from the compatibility tables generated by manufacturers of elastomers or polymers used in o-rings, gaskets, seals, etc.
** Vendor model solvent data can be used, if there is no risk
*** Information and data provided by filter manufacturer